The lysine 831 of vascular endothelial growth issue receptor 1 is a novel target of methylation by SMYD3. Methylation of proteins from budding yeasts (corresponding to Ipl Aurora kinase and ribosomal proteins) and vegetation (Rubisco subunits) has also been reported eleven , 183 - 185 It is conceivable that many proteins may be modified by lysine methylation, along with different varieties of PTMs. The lysine demethylase LSD1 (KDM1) is required for maintenance of global DNA methylation.

Methylation been discovered on a spread of lysine residues in various histones: K4 (utilizing the only-letter amino-acid code for lysine), K9, K27, K36 and K79 in histone H3, K20 in histone H4, K59 in the globular area of histone H4 2 and K26 of histone H1B 3 Several proteins accountable for the methylation of specific residues have been characterized, and all but one in every of these contains a SET area